Design and synthesis of novel bis-annulated caged polycycles via ring-closing metathesis: pushpakenediol

• Sambasivarao Kotha and
• Mirtunjay Kumar Dipak

Beilstein J. Org. Chem. 2014, 10, 2664–2670, doi:10.3762/bjoc.10.280

• rearrangement, a ring-closing metathesis (RCM) and an alkenyl Grignard addition. The introduction of olefinic moieties in the pentacycloundecane (PCUD) framework at appropriate positions followed by RCM led to the formation of novel heptacyclic cage systems. Keywords: Diels–Alder cycloaddition; Grignard

• addition; pentacycloundecane (PCUD); ring-closing metathesis; Introduction Caged polycyclic compounds draw the attention of synthetic organic chemists due to their unusual reactivity patterns as well as their strained nature [1][2][3][4][5][6][7][8][9]. Several pentacycloundecane (PCUD) related molecules